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Metformin and Diabetic Drugs Increase Mortality

Why do Type 2 (adult-onset) diabetics have high blood sugar?  Is it because they are lacking a prescription drug that lowers blood sugar levels?  Of course not.  Diabetics have elevated blood sugars because they have hormonal and nutritional imbalances often caused by eating an unhealthy diet.  The conventional treatment for diabetes revolves around giving poor dietary advice–eat low-fat foods with lots of carbohydrates and use toxic artificial sweeteners– and the use of prescription medications that do not treat the underlying cause of diabetes.

A recent article titled, “14-Year Risk of All-Cause Mortality According to Hypoglycemic Drug Exposure in a General Population” assessed the safety data of diabetic drugs over a 14-year time period. (1)  The authors studied 3336 participants and 248 deaths over a 14-year time period. 

The scientists compared the all-cause mortality risk in non-diabetic versus diabetic subjects.   The found that untreated diabetics had a 222% increase risk of all-cause mortality.  Diabetics treated with Metformin had 128% increase risk of death.  Diabetics treated with sulfonylureas (e.g., Glyburide, Amaryl, Glucotrol, Glynase, DiaBeta) had a 70% increase in all-cause mortality.  Diabetics treated with insulin had 329% increase in all-cause mortality. 

Folks, these numbers should not be shocking.  Conventional medicine has been focused on chemically lowering blood sugar numbers for many years.  However, the elevated blood sugar numbers are not the problem in diabetes.  They are the symptom that something is wrong in the body.  Another way to look at elevated blood sugar is that it is the “idiot light” telling you that something is wrong in the body.  

I am not saying that a type 1 diabetic does not need insulin; of course they do.  Type 1 diabetics do not produce enough insulin.  However, adult –onset diabetes, which is much more common, is generally not caused by a lack of insulin production.  It is caused by eating a poor diet lacking basic nutritional items and containing too much refined sugar.  This throws off the body’s ability to maintain adequate blood sugar control and the serum blood sugar rises.  What is the solution?  Eat a better diet, free of refined food and avoid all refined sugar.  Eliminating all grains help.  Correcting nutritional and hormonal imbalances further improves the condition.   And, exercise also improves the diabetic condition. 

It is sad that conventional medicine spends so much money on using ineffective drugs that do not treat the underlying cause of the problem. Diabetes is just another example of conventional medicine not addressing the underlying cause of illness.   

More information about this can be found in my book, Drugs That Don’t Work and Natural Therapies That Do.



Author Info

David Brownstein

Comments ( 7 )

  • Author Icon
    Bonnie Cole

    Hello :

    I recently posted on the benefits of using Berberine instead of Metformin after reading
    Dr. Jonathan Wright’s newsletter in March and my post disappeared. Is it okay to post it here?


  • Author Icon

    The Life Extension Foundation and Dr. Ward Dean promote metformin as a life extension agent.

  • Author Icon

    A 3.22 fold increase is the same as a 222% increase.

    Would it not be clearer to say “A 3.22 fold factor is the same as a 222% increase”? The word “increase” implies an amount in addition to what was there before. To illustrate, consider a measure that goes from 100 to 89. That is NOT a “.89 fold increase”; it’s a “.89 fold factor”.

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    In your article you talk about a 3.22 fold increase and a 128% increase. Can you explain how these two numbers relate to each other.
    Greg Penniston, DC

    • Author Icon
      David Brownstein

      Dr. Penniston,
      A 3.22 fold increase is the same as a 222% increase. I am sorry for the confusion, I was just trying to report it in different ways–all making the same point. I will edit it and put both numbers in.

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    Lisa Ostendorf

    I agree that a diet high in carbs and sugar is a huge contributing factor in causing Type 11 diabetes, however,
    it would be great to address, in more detail, the hormonal imbalances that also influence it. My husband
    eats hardly any carbs and basically no sugar, and still has elevated blood sugar. I am trying to get him to
    balance his hormones, but this is difficult as he and basically everyone else, does not understand the correlation
    and importance of it. Would love to hear more info. about that.
    Thanks Dr. Brownstein!

  • Author Icon

    Thank you for this article. My FNP tried to put me on metformin ( I am not diabetic) . I refused and chose to reduce the calcium channel blocker I was taking and work on diet and exercise. She did not even suggest this. Very disheartening when you can’t find a medical provider you can trust. They are all just drug pushers

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